The Global Proteome Machine Organization

  The Global Proteome Machine Organization
  Proteomics Database and Open Source Software
  www.thegpm.org

    GPMDB Video Tutorials

The GPMDB contains thousands of data sets contributed by researchers around the world. The large volume of data and biological complexity means that it can be a little intimidating for first time users to figure out how to extract information form the database. This page contains our video tutorials for using the system, presented as a set of case studies and discussions.

    Case: Finding phosphorylation sites using GPMDB and pSYT

This video describes the steps necessary to find the observed phosphorylation sites for a particular protein. The description is in the form of a dialogue between a biomedical researcher (as played by HRM Queen Elizabeth II) and a GPMDB power user (Beavo the clown). Together, they get the researcher started obtaining the phosphorylation sites for her protein of interest C21orf66 and its corresponding pSYT entry.

    Discussion: Interpreting details found in high-throughput data

Santa and Hillary discuss the difficulties of assigning specific post-translational modifications and alternately spliced protein sequences from high throughput data and give some advice. The script was adapted from our list of suggested interpretation guidelines.




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